基本情况
姓名：吴凯
性别：男
籍贯：河南驻马店
职位：教授，博士生导师
联系方式
邮箱：wukai9@mail.sysu.edu.cn
通讯地址：广州市番禺区大学城外环东路132号中山大学化学材料综合楼
个人主页：https://orcid.org/0000-0001-6336-7836
教育经历
2013.8‒2018.6，中山大学，博士，物理化学，导师：苏成勇教授
2009.8‒2013.6，兰州大学，本科，化学（国家基础科学人才培养基地），导师：王为教授
工作经历
2024.1–至今，中山大学化学学院，教授，博士生导师
2021.7‒2024.1，剑桥大学化学系，ERC博士后研究员，合作导师：Prof. Jonathan Nitschke（Fellow of the European Academy of Sciences，Head of Materials Chemistry）
2018.10‒2021.6，多特蒙德工业大学，ERC博士后研究员，合作导师：Prof. Guido Clever（Vice Dean, Chair of Bioinorganic Chemistry）
讲授课程
本科生：学术写作与交流Academic Writing and Communication（强基班），现代化学研究方法与实验I&II（强基班）
学生培养
2025 中山大学优秀本科毕业论文，2021级本科生贺加贝
2025 中山大学大学生创新训练项目，2022级强基王思婷
2022 合作指导的剑桥大学硕士生Leonard Goh，获得Johnson Matthey Prize (Best inorganic project，学院仅1人/年)
2020 Subgroup leader (Supervised 2 PDRA, 3 Ph.D. candidates)
科研方向
- 仿酶仿生配位笼精准组装与多功能集成
- “活性”异金属笼功能化设计
课题组长期招聘博士后和专职科研系列人员。欢迎具有超分子化学、配位化学、晶体学等相关研究背景人员应聘。同时欢迎本科生、夏令营学生到课题组学习，研究生名额充足，硕士、博士研究生报考。
特别优秀的后续可以推荐到英国剑桥大学、德国等高校继续深造。团队依托诺贝尔奖得主、超分子化学之父Jean-Marie Lehn命名的Lehn功能材料研究所（LIFM）与剑桥大学Jonathan Nitschke教授联合招收博士研究生和博士后研究员（参见详细信息）。
科研项目
8. 2025年度中山大学青年科学家培育项目（2025.1–2027.12，24hytd004-2，120万，主持）
7. 广东省“珠江人才计划”引进创新创业团队项目（2024.9–2029.9，2023ZT10L061，1000万，子项目负责人）
6. 国家自然科学基金重大研究计划项目团簇构造、功能及多级演化集成项目（2025.1–2027.12，92461302，316万，核心成员）
5. 国家自然科学基金青年科学基金项目（2025.1–2027.12，22401299，30万，主持）
4. 广东省自然科学基金面上项目（2025.1–2027.12，2025A1515011427，10万，主持）
3. 国家自然科学基金优秀青年科学基金项目（海外）（2024.12–2027.12，2023HY19241206，100万，主持）
2. 中山大学引进人才基本启动费（2024.5–2027.12，主持）
1. 高校基本科研业务费中山大学优秀青年科学基金（2024.1–2026.12，24hytd004，主持）
获奖情况
2024 英国皇家化学会会员Member of the Royal Society of Chemistry (MRSC)
2024 逸仙学者计划“优秀学者”
2023 国家海外高层次青年人才
2018 英国皇家学会–王宽诚基金会国际奖学金
2017 芙兰学生优秀论文奖学金
2016 博士研究生国家奖学金
2016 第7届全国物理无机化学学术会议优秀海报奖
2014 安婕妤奖学金
论著一览
围绕配位超分子自组装，系统研究了“可控自组装策略的发展”及“配位限域空间多功能集成与性能调控”两个关键科学问题；致力于揭示配位超分子体系可控自组装、结构多样性与构效关系的内在规律，沿着“可控自组装策略发展→结构多样性设计→构效关系研究→多功能集成与性能调控”的研究思路，开展了以结构多样性配位笼为平台，配位限域空间多功能化为应用导向核心的组装与性能研究，取得了一系列突出的创新性研究成果，迄今共发表SCI论文42篇，以通讯、第一作者发表论文12篇，包括Nat. Chem.（高被引）、Nat. Synth.、Natl. Sci. Rev.、Nat. Commun.、J. Am. Chem. Soc.（2篇）、Angew. Chem. Int. Ed.（4篇）、Sci. China Chem.等，论文引用总次数3,000余次，H因子25。相关研究被Nature Research Communities、剑桥大学化学院新闻网、ChemistryViews、Chem等进行了亮点报道，并得到了EurekAlert、Science Daily、Phys.org、The Medical News、DeepTech等多家科学媒体的转载及全球知名医药行业杂志The Medicine Maker的专访
Google Scholar: https://scholar.google.com/citations?user=r1EhFRcAAAAJ&hl=en
Scopus: https://www.scopus.com/authid/detail.uri?authorId=58059437100
代表论著：
2025
23. J.-B. He‡, E. Benchimol‡, W.-J. Zhang‡, S.-T. Wang, K. Wu*, Guido H. Clever*, Diversification of heteroleptic assembly topologies through covalent bridging, In Submission.
22. K. Wu, C.-Y. Su*, Induced-fit expansion and contraction of a pseudo-cubic host switch from endo to exo upon binding large guests,Sci. China. Chem.2025, 68, 1627–1629.
21. X. Sun, K. Wu, P. C. P. Teeuwen, P. Pracht, D. J. Wales*, J. R. Nitschke*, Proton-driven lithium separation using alkali-templated coordination cages, Chem2025, 11, 102556.
2024
20. Y.-L. Lu, K. Wu*, Y.-H. Huang, W.-C. Li, Z.-M. Cao, X.-H. Yan, X.-D. Zhang, C.-H. Liu, J. Ruan, H.-S. Xu, M. Pan, C.-Y. Su*, Stereochemical Control of Redox CoII/CoIII-Cages with Switchable Cotton Effects Based on Labile-Static States,J. Am. Chem. Soc.2024, 146, 20414–20424.
(Highlighted byX-MOL)
19. K. Wu, E. Benchimol, A. Baksi, G. H. Clever*, Non-statistical assembly of Multicomponent [Pd2ABCD] Cages, Nat. Chem. 2024, DOI: 10.1038/s41557-023-01415-7. (Highlighted by Nature Research Communities, Chem, ChemistryViews, Polysci, Preprint: ChemRxiv, 2023, DOI: 10.26434/chemrxiv-2023-5gb4q)
2023
18. K. Wu, T. K. Ronson, P. Su, Z. Chen, L. Goh, A. W. Heard, X. Li, F. Klautzsch, C. A. Schalley, M. Vinković, J. R. Nitschke*, Systematic construction of progressively larger capsules from a fivefold linking pyrrole-based subcomponent, Nat. Synth. 2023, 2, 789–797. (Highlighed by University of Cambridge, The Medicine Maker, ChemistryViews, EurekAlert, Science Daily, Phys.org, The Medical News, X-MOL, DeepTech)
17. K. Wu, T. K. Ronson, L. Goh, W. Xue, A. W. Heard, P. Su, X. Li, M. Vinković, J. R. Nitschke*, A Diverse Array of Large Capsules Transform in Response to Stimuli, J. Am. Chem. Soc. 2023, 145, 11356–11363.
2022
16. K. Wu‡, J. Tessarolo‡, A. Baksi, G. H. Clever*, Guest-modulated Circularly Polarized Luminescence by Ligand-to-Ligand Chirality Transfer in Heteroleptic Pd(II) Coordination Cages, Angew. Chem. Int. Ed. 2022, 61, e202205725. (Hot paper, Front Cover)
15. K. Li‡,K. Wu‡, C.-Y. Su* et al. Creating Dynamic Nanospaces in Solution by Cationic Cages as Multirole Catalytic Platform for Unconventional C(sp)-H Activation Beyond Enzyme Mimics, Angew. Chem. Int. Ed. 2022, 61, e202114070. (Hot paper, Frontispiece, Highlighted in SYNFACTS 2022, 18, 0414)
14. K. Li‡, K. Wu‡, Y.-Z. Fan‡, J. Guo, Y.-L. Lu, Y.-F. Wang, G. Maurin, C.-Y. Su*, Acidic Open-cage Solution Containing Basic Cage-confined Nanospace for Multipurpose Catalysis, Natl. Sci. Rev. 2022, 9, nwab155. (Article, Highlighed by EurekAlert! (AAAS). Ranking # 4 out of 73 in multidisciplinary sciences)
2021
13. K. Wu, B. Zhang, C. Drechsler, J. J. Holstein, G. H. Clever*, Backbone‐Bridging Promotes Diversity in Heteroleptic Cages, Angew. Chem. Int. Ed. 2021, 60, 6403–6407. (Hot paper)
Before 2020
12. K. Wu‡, K. Li‡, S. Chen, Y.-J. Hou, Y.-L. Lu, J.-S. Wang, M.-J. Wei, M. Pan, C.-Y. Su*, The Redox Coupling Effect in a Photocatalytic Ru(II)-Pd(II) Cage with TTF Guest as Electron Relay Mediator for Visible-Light Hydrogen-Evolving Promotion, Angew. Chem. Int. Ed. 2020, 59, 2639–2643. (VIP paper, Inside back cover, Highlighted on Acta Physico-Chimica Sinica, X-mol.com)
11. K. Wu‡,K. Li‡, Y.-J. Hou, M. Pan*, L.-Y. Zhang, L. Chen, C.-Y. Su*, Homochiral D4-symmetric Metal-organic Cages from Stereogenic Ru(II) Metalloligands for Effective Enantioseparation of Atropisomeric Molecules. Nat. Commun. 2016, 7, 10487.
10. K. Wu, Y.-J. Hou, Y.-L. Lu, Y.-Z. Fan, Y.-N. Fan, H.-J. Yu, K. Li, M. Pan*, C.-Y. Su, Redox-Guest-Induced Multimode Photoluminescence Switch for Sequential Logic Gates in a Photoactive Coordination Cage, Chem. Eur. J. 2019, 25, 11903–11909.
9. M. Pan, K. Wu, J.-H. Zhang, C.-Y. Su*, Chiral Metal-organic cages/containers (MOCs): From Structural and Stereochemical Design to Applications, Coord. Chem. Rev. 2019, 378, 333–349. (Listed as “High-cited papers” in Web of Science)
8. Y.-J. Hou, K. Wu, Z.-W. Wei, K. Li, Y.-L. Lu, C.-Y. Zhu, J.-S. Wang, M. Pan, J.-J. Jiang, G.-Q. Li, C.-Y. Su*, Design and Enantioresolution of Homochiral Fe(II)–Pd(II) Coordination Cages from Stereolabile Metalloligands: Stereochemical Stability and Enantioselective Separation,J. Am. Chem. Soc. 2018, 140, 18183–18191.
7. J.-S. Wang, K. Wu, C. Yin, K. Li, Y. Huang, J. Ruan, X. Feng, P. Hu*, C.-Y. Su*, Cage-confined Photocatalysis for Wide-scope Unusually Selective [2+2] Cycloaddition through Visible-light Triplet Sensitization, Nat. Commun. 2020, 11, 4675.
6. W. Xue, K. Wu, N. Ouynag, T. Brotin, J. R. Nitschke*, Allosterically Regulated Guest Binding Determines Framework Symmetry for an FeII4L4 Cage, Angew. Chem. Int. Ed. 2023, 135, e202301319.
5. Y.-P. Wang, K. Wu, M. Pan*, K. Li, J.-T. Mo, X.-H. Duan, H.-Z. He, J. Shen*, C.-Y. Su*, One-/Two-Photon Excited Cell Membrane Imaging and Tracking by a Photoactive Nanocage, ACS Appl. Mater. Interfaces 2020, 12, 35873–35881.
4. M. Pan, Y.-X. Zhu, K. Wu, L. Chen, Y.-J. Hou, S.-Y. Yin, H.-P. Wang, Y.-N. Fan, C.-Y. Su*, Epitaxial Growth of Hetero-Ln-MOF Hierarchical Single-Crystals for Domain- and Orientation-Controlled Multi-color Luminescence 3D Coding Capability, Angew. Chem. Int. Ed. 2017, 56, 14582–14586.
3. J. Guo, Y.-W. Xu, K. Li, L.-M. Xiao, S. Chen, K. Wu, X.-D. Chen, Y.-Z. Fan, J.-M. Liu*, C.-Y. Su*, Regio- and Enantioselective Photodimerization within the Confined Space of a Homochiral Ruthenium/Palladium Heterometallic Coordination Cage, Angew. Chem. Int. Ed. 2017, 56, 3852–3856.
2. Q.-Y. Yang, K. Wu, J.-J. Jiang, C.-W. Hsu, M. Pan*, J.-M. Lehn, C.-Y. Su*, Pure White-light and Yellow-to-Blue Emission Tuning in Single Crystals of Dy(III) Metal–organic frameworks, Chem. Commun. 2014, 50, 7702–7704.
1. S.-R. Zheng, M. Pan*, K. Wu, L. Chen, J.-J. Jiang*, D.-W. Wang, J.-Y. Shi, C.-Y. Su, Assembly of Binuclear, Tetranuclear, and Multinuclear Complexes from Pincer-like Mononuclear Metallotectons: Structural Diversity Dependent on Precursors, Cryst. Growth Des. 2015, 15, 625–634.
