2018年10月8日英国南安普顿大学Stephen M. Goldup教授学术报告

Synthesis and Applications of “Mechanically” Chiral Molecules

发布人:高级管理员 发布日期:2018-09-26
主题
Synthesis and Applications of “Mechanically” Chiral Molecules
活动时间
-
活动地址
丰盛堂芙兰学术中心A403
主讲人
Stephen M. Goldup教授 英国南安普顿大学
主持人
朱克龙教授

报告摘要:

Interlocked molecules can display forms of stereochemistry that do not rely on classical covalent stereogenic units.  Our group have pioneered the use of “small” macrocycle ,  mediated active template  reactions in order to allow the synthesis of challenging interlocked structures, for applications in sensing  and catalysis.  Here we describe recent progress in the stereoselective active template synthesis of enantiopure mechanically planar chiral rotaxanes (a)  and topologically chiral catenanes (b)  for a range of applications.

 

报告人简介:

Dr. Stephen Goldup initially trained in Natural Product synthesis before shifting focus to apply  his  synthetic training  to  the  realization  of  mechanically interlocked  non-natural  products  during  his postdoctoral  studies.  In  2008  he moved to Queen Mary University of London (QMUL) with the award of a Leverhulme Trust Early Career Fellowship and began his fully independent research career in 2009 with the award of a prestigious Royal Society University Research Fellowship. In 2014 he was appointed as Associate Professor of Organic Chemistry and Royal Society Research Fellow at the University of Southampton.